I wanted to share with you something that I've become more sensitized to, and see if any of you have encountered this in your practices. I've attached a background article that Carole Hong and I recently co-authored, at the end of which I mentioned PANDAS. This is an acronym for:
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus. You can read more about it at:
What intrigued me is a book that is currently on the NY Times bestseller list, called "Saving Sammy". It is an incredible book that I'd urge you to buy and read cover-to-cover. While it's easy to over-extrapolate the prevalence of untreated strep infections, it isn't easy to over-extrapolate the significance of treating it. And in this case, it seems like getting a child started on Augmentin is extremely helpful - but recovery is years in the making once the brain has been damaged by the persistent untreated strep cycles (which show up on high strep titers, if physicians do the blood workup for it).
The reason I'm writing is that I saw a child last week who was "diagnosed" as having a rare disorder, known as Landau-Kleffner, which is now felt to be part of the Autistic Spectrum. However, his profile of relatively sudden onset signs matches PANDAS almost exactly.
So .... anyone out there have personal experience with "PANDAS" among your patients?